SKIN QUALITY INJECTABLES · TREATMENT
Polynucleotide treatments
Polynucleotides (PN) are purified chains of DNA building blocks used in some skin injections. Early studies suggest possible changes in hydration and texture; this does not mean they repair your DNA or regenerate your skin.
Is it right for me?
A consultation may be useful for fine crepiness or delicate skin concerns. Ingredient source, fish-related allergies where relevant, and previous reactions need discussion.
Discuss allergies, previous injectables, active infection, medicines and any healing problems. Tell the clinician if you are pregnant or breastfeeding; elective treatment may need to be deferred because safety information is limited. Do not stop prescribed medicines without advice from the prescriber.
Evidence and realistic expectations.
In a small randomized study of 27 people, PN was compared with HA near the eyes. Some skin measurements favored PN, while overall aesthetic ratings did not clearly separate the treatments. Larger, longer studies are needed.
PN and PDRN describe related but different preparations and cannot be treated as interchangeable. Results from wound-healing or laboratory research do not establish cosmetic benefit. Evidence does not support a guaranteed cure for dark circles.
Risks to understand.
Injection-site bumps, bruising, swelling, infection or an inflammatory reaction can occur. The proposed product, its ingredients and the risks for the treatment area should be discussed before proceeding.
What to expect.
Consultation
Discuss your concern, medical history, previous treatments and what you would like to preserve. Dr. Roy will explain suitable options, alternatives, risks and fees before you decide.
Treatment
After assessment, Dr. Roy explains the preparation, its source and the proposed treatment area. If you choose to proceed, selected skin injections are followed by aftercare and a review plan.
Recovery
Bumps, bruising or swelling can be visible after treatment. The eye area may remain swollen longer than other areas.
Results and review
Changes, when present, are gradual over weeks. Assessment may extend across roughly one to three months; response is not assured.
Number of visits
A course may involve several visits, with the final schedule determined by the formulation and your response.
Good questions.
Clearer decisions.
What can polynucleotide treatments address?
Fine crepiness and selected skin-quality concerns. Polynucleotides (PN) are purified chains of DNA building blocks used in some skin injections. Early studies suggest possible changes in hydration and texture; this does not mean they repair your DNA or regenerate your skin.
Who might be a suitable candidate?
A consultation may be useful for fine crepiness or delicate skin concerns. Ingredient source, fish-related allergies where relevant, and previous reactions need discussion.
What happens during the appointment?
After assessment, Dr. Roy explains the preparation, its source and the proposed treatment area. If you choose to proceed, selected skin injections are followed by aftercare and a review plan.
How much recovery time should I allow?
Bumps, bruising or swelling can be visible after treatment. The eye area may remain swollen longer than other areas.
When could I see a change?
Changes, when present, are gradual over weeks. Assessment may extend across roughly one to three months; response is not assured.
How many visits might I need?
A course may involve several visits, with the final schedule determined by the formulation and your response.
Are polynucleotides the same as exosomes or stem cells?
No. PN products contain chains of nucleotides; exosomes are tiny cell-released particles, and secretomes are mixtures of cell-released substances. None of those terms is interchangeable with a treatment containing living stem cells.
What is the cost of polynucleotide treatments?
Contact the clinic for current fees. Ask for the price of the consultation, each proposed treatment, any planned review and any optional additional steps before deciding. No fixed fee is published on this page.
General patient information. A consultation is needed to determine your suitability. Treatment choices and outcomes vary.
Further reading: Small randomized study of PN and HA near the eyes. These sources do not endorse the clinic. Regulatory information from other countries is identified as such.
Evidence and copy checked 2026-09-16.
Related care.
Request a consultation.
Ask about polynucleotide treatments with Dr. Roy. Choose your topic, then review and send your request on WhatsApp.
A conversation first.
Take the time you need.
A consultation is a chance to discuss options, risks and costs. You can ask about a simpler plan or decide not to proceed.